Condylomata acuminata and human genital cancer.

نویسنده

  • H zur Hausen
چکیده

1. Almeida, J. D., Oriel, J. D., and Stannard, L. M. Characterization of the Virus Found in Human Genital Warts. Microbios, 3: 225-232, 1969. 2. Bauer, K. M., and Friederich H. C. Peniscarcinom auf dem Boden vorbehandelter Condylomata acuminata. Z. Haut-Geschlechlskrankh., 39:150-163, 1965. 3. Dawson, D. F., Duckworth, J. K., Bernhardt, H. and Young, J. M. Giant Condyloma and Verrucous Carcinoma of the Genital Area. Arch. Pathol., 79: 225-231, 1965. 4. Domaniewski, J., and Gustowski, A. Planoepithelial, Spinocellular Cancer of the Vulva, Originating from Condylomata Acuminata. Ginekol. Pol., 39: 239-242, 1968. 5. Dunn, A. E. G., and Ogilvie, M. M. J. Ultrastruct. Res., 22: 282-291,1968. 6. Frenkel, N., Roizman, B., Cassai, E., and Nahmias, A. J. DNA Fragment of Herpes Simplex 2 and Its Transcription in Human Cervical Cancer Tissue. Proc. Natl. Acad. Sci. U. S., 69: 3784-3789, 1972. 7. Friedberg, M. J., and Serlin, O. Condyloma acuminatum: Its Association with Malignancy. Diseases Colon Rectum, 6: 352-355, 1963. 8. Goldberg, R. J., and Gravell, M. A Search for Herpes Simplex Virus Type 2 Markers in Cervical Carcinoma. Cancer Res., 36: 795-799, 1976. 9. Grussendorf, E. J., and Gahlen, W. Morbus Bowen bei Condylomata Acuminata (Zur Frage der M~)glichkeit Virus-bedingter Tumorinduktion). Hautarzt, 25: 443-447, 1974. 10. Kerl, H., and Pickel, H. Maligne Umwandlung yon Condylomata Acuminata der Vulva. Z. HautGeschleschlskrankh., 46: 155-162, 1971. 11. MacDonald, C. Venereal Wart Converted into a Carcinoma by Cauterization. Illinois Med. J., 40: 230, 1921. 12. Nahmias, A. J., Josey, W. E., Naib, Z. M., Luce, C. F., and Guest, B. A. Antibodies to Herpes Hominis Types 1 and 2 in Humans. I1. Women with Cervical Cancer. Am. J. Epidemiol., 91: 547-552, 1970. 13. Oriel, J. D., and Almeida, J. D., Demonstration of Virus Particles in Human Genital Warts. Brit. J. Venereal Diseases, 46: 37-42, 1970. 14. Rawls, W. E., Tompkins, W. A. F., and Melnick, J. L. The Association of Herpesvirus Type 2 and Carcinoma of the Uterine Cervix. Am. J. Epidemiol., 89: 547-554, 1969. 15. Siegel, A. Malignant Transformation of Condyloma Acuminatum. Am. J. Surg., 103: 613-617, 1962. 16. Sims, C. F., and Garb, J. Giant Condyloma Acuminatum of Penis Associated with Metastatic Carcinoma of Right Inguinal Lymph Node. Arch. Dermatol. Syphilis, 63: 383-390, 1951. 17. Sonck, C. E. Condyloma Accuminata mit Ubergang in Karzinom. Z. HautGeschlechlskrankh., 46: 273-278, 1971. 18. Wolf, F. In die Tiefe wuchernde spitze Condylome und Carcinom in demselben Penis-Tumor. Z. Haut-Geschlechlskrankh., 13: 142-144, 1952. 19. zur Hausen, H. Oncogenic Herpes Viruses. Biochim. Biophys. Acta, 417: 25-53, 1975. 20. zur Hausen, H., Meinhof, W., Scheiber, W., and Bornkamm, G. W. Attempts to Detect Virus-specific DNA Sequences in Human Tumors: I. Nucleic Acid Hybridizations with Complementary RNA of Human Wart Virus. Intern. J. Cancer, 13: 650L656, 1974. 21. zur Hausen; H., Schulte-Holthausen, H., Wolf, H., DOrries, K., and Egger, H. Attempts to Detect Virus-specific DNA Sequences in Human Tumors: I1. Nucleic Acid Hybridizations with Complementary RNA of Human Herpes Group Viruses. Intern. J. Cancer, 13: 657-664, 1974.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Condylomata acuminata and risk of cancer: an epidemiological study.

OBJECTIVE To determine whether patients with condylomata acuminata have an increased risk of developing cancer. DESIGN Prospective cohort study on patients diagnosed as having condylomata acuminata. The number of malignant tumours in the cohort was compared with national incidences obtained from the Swedish Cancer Registry. SETTING Dermatology department of the Karolinska Hospital, Stockhol...

متن کامل

Human Papillomavirus Infection.

Condyloma acuminata, the anogenital expression of human papillomavirus commonly called genital warts, is the focus here. Of particular emphasis is HPV's association with genital cancer. The use of androscopy for the examination and treatment with cryotherapy, podophyllin, trichloroacetic acid, and 5-fluorouracil also are assessed.

متن کامل

Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients.

Condylomata acuminata, or genital warts, are proliferative lesions of genital epithelium caused by human papillomavirus (HPV) infection. HPV types 6 and 11 are most often detected in these lesions. Genital lesions consistent with exophytic condylomata acuminata were removed by excision biopsy from 65 patients, 41 of whom were otherwise healthy individuals (control group) and 24 of whom had cond...

متن کامل

Local accumulation of FOXP3+ regulatory T cells: evidence for an immune evasion mechanism in patients with large condylomata acuminata.

Condylomata acuminata derived from the infection of human papillomavirus is a common sexually transmitted disease. Although T cell-mediated cellular immunity is considered as the main arm against such infection, the regulation of T cell immune responses in genital condylomata is unclear to date. In this study, we analyzed FOXP3(+) regulatory T cells in genital condylomata of patients. The resul...

متن کامل

Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia

Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A 42-year-old male presented with pain and foul-smelling discharge from his genital warts. The his...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Cancer research

دوره 36 2 pt 2  شماره 

صفحات  -

تاریخ انتشار 1976